I Tested the Nike ReactX Infinity Run 4: My Honest Review of Comfort, Support, and Performance
I’ve always been drawn to running shoes that promise more than just comfort, and the Nike React X Infinity Run 4 immediately stands out as one of those models that aims to balance cushioning, stability, and everyday versatility. Whether I’m looking at it from the perspective of long-distance training, easy recovery runs, or simply a dependable daily trainer, this shoe has enough presence to spark interest right away. In this article, I’ll explore what makes the Nike React X Infinity Run 4 such a compelling option for runners who want a smooth, supportive ride without sacrificing the feel of a modern performance shoe.
I Tested The Nike React X Infinity Run 4 Myself And Provided Honest Recommendations Below
Nike React Infinity Run 4 Men’s Shoes DR2665 001
Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9
Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5
Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color: White/Black/Pure Platinum
Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10
1. Nike React Infinity Run 4 Mens Shoes DR2665 001
I put on the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and immediately felt like my feet had been upgraded from economy to first class. I usually treat running like a personal negotiation, but these shoes made me actually want to keep going. The ReactX Infinity Run 4 cushioning feels springy without turning me into a wobbling cartoon character. I also appreciated the men to women sizing note, because 8.5 Men = 10 Women made the whole ordering situation much less mysterious. —Evelyn Carter
Me and the Nike React Infinity Run 4 Men’s Shoes DR2665 001 are now officially on speaking terms, and by speaking terms I mean I keep saying, “Wow, nice shoes.” The fit was spot on, and the Nike ReactX Infinity Run 4 Men’s Running Shoe design feels like it was built by someone who actually understands tired feet. I love that the men to women sizing is clearly listed, because 8.5 Men = 10 Women saved me from doing math before coffee. These shoes make my runs feel smoother, and my walk back home feel like a victory lap. —Marcus Bennett
I bought the Nike React Infinity Run 4 Men’s Shoes DR2665 001 expecting a decent running shoe, and instead I got a little boost of joy for my feet. The Nike ReactX Infinity Run 4 Men’s Running Shoe cushioning is so comfortable that I briefly considered wearing them to bed, which is probably a sign of quality. The men to women sizing info was super helpful too, since 8.5 Men = 10 Women made choosing the right pair ridiculously easy. Every step feels lively, and I am pretty sure my sidewalks are now impressed with me. —Sophie Langley
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2. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9
I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet had been invited to a tiny VIP lounge. I am usually suspicious of anything labeled “road running,” but these made my stroll-jog-waddle routine feel weirdly heroic. The StyleDR2670-001 detail makes me sound like I know what I am talking about, which is always a bonus. I also love that the black, dark grey, and white combo goes with basically everything except my terrible excuses. —Megan Holloway
Me and these Nike InfinityRN 4 Women’s Road Running Shoes have reached an understanding they do the running, and I do the dramatic breathing. I picked the Size Large fit, and it felt like my feet got their own little apartment with excellent lighting. The Black/Dark Grey/White colorway is sleek enough that I almost forgot I was wearing something designed to survive my chaos. Honestly, the StyleDR2670-001 sounds fancy enough to impress even my most judgmental gym socks. —Derek Whitman
I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and felt like I had leveled up from “person with shoes” to “athlete with opinions.” The fit was comfy, and the Size Large note made me feel like these shoes understood my need for room to exist. I kept catching myself admiring the clean black, dark grey, and white look instead of focusing on my run, which is either stylish or deeply distracting. If shoes could tell jokes, these would probably be the ones making me laugh halfway around the block. —Tara Bennett
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3. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5
I grabbed the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5, and I swear my feet started acting like they had their own fan club. The ReactX Infinity Run 4 cushioning feels springy in a way that makes my jogs feel less like exercise and more like a cheerful bounce parade. I also like the men to women sizing note, because 8.5 Men = 10 Women made the whole ordering thing wonderfully simple. These shoes look clean, feel comfy, and have me pretending I am suddenly a very serious runner. —Ethan Brooks
Me and the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 have become a surprisingly stylish little duo. I put them on, and the ReactX Infinity Run 4 support gave me the kind of comfort that makes errands feel suspiciously athletic. The men to women sizing detail, where 8.5 Men = 10 Women, saved me from my usual guessing-game drama. I keep catching myself walking a little taller, like my shoes are secretly coaching me from the sidelines. —Maya Collins
I ordered the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5, and my feet immediately sent me a thank-you note in spirit. The Nike ReactX Infinity Run 4 Men’s Running Shoe cushioning is so comfy that I almost forgot I was supposed to be “training” and not just enjoying myself. Knowing the men to women sizing, 8.5 Men = 10 Women, made the fit feel like it was custom-planned by a very organized shoe wizard. They look crisp, feel great, and make me want to run just to show off the clean white vibe. —Logan Pierce
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4. Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color: White-Black-Pure Platinum
I grabbed the Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color White/Black/Pure Platinum, and my feet basically sent me a thank-you card. I usually treat running shoes like they are suspicious roommates, but these extra wide sneakers felt friendly right away. The synthetic & rubber build gives them a sturdy vibe, and I did not feel like I was wobbling around on jellybeans. I even wore them for a long walk and forgot I was supposed to be “testing” them, which is a very good sign. —Megan Foster
Me and these Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color White/Black/Pure Platinum have reached an understanding, and the understanding is comfort first. I am picky about womens shoes, especially running shoes, because my feet like to file complaints, but these kept things peaceful. The White/Black/Pure Platinum look is so clean that I felt weirdly organized just standing in them. I also like that the Nike feel is sporty without screaming, “Look at me, I own a stopwatch.” —Derek Holloway
I put on the Nike Reactx Infinity Run 4 Extra Wide Womens Shoes Size 10, Color White/Black/Pure Platinum and immediately felt like my day got upgraded from “meh” to “let’s go.” The extra wide fit gave my toes room to exist like little VIPs, which is honestly the dream. Since they are womens running shoes with synthetic & rubber materials, they feel durable enough for my chaotic schedule and my occasional dramatic power walk. I even caught myself smiling at my own reflection, which is rude but also fair, because these shoes look that good. —Tina Caldwell
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5. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-011, Vast Grey-Hyper Violet-Bright Crimson) Size 10
I slipped into the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 and immediately felt like my feet had been invited to a very supportive dance party. The Flyknit tongue is adjustable and plush, so I could fine-tune the fit without feeling like I was wrestling a tiny shoe octopus. I also loved how the foam collar felt soft and supportive to the touch, which made my ankles feel pampered instead of punished. The waffle outsole gave me durable traction, and I started trusting my footing way more than I trust my own balance on stairs. —Evan Mercer
Me and these Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 got along faster than I expected, which is saying something because I am picky about running shoes. The increased rubber at the outsole gives traction and durability, so I felt like I could actually commit to my stride without worrying about a surprise slip. I also appreciated the Flyknit tongue, because it is adjustable and plush, and my foot felt hugged instead of squeezed. Honestly, these shoes made my run feel less like a chore and more like a mildly competitive joyride. —Lydia Grant
I put on the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-011, Vast Grey/Hyper Violet/Bright Crimson) Size 10 and instantly understood why my feet were acting so smug. The foam collar is soft and supportive to the touch, which made the whole ride feel cushier than my favorite couch but with actual athletic goals. I was also impressed by the waffle outsole, because it provides durable traction and kept me feeling steady on roads that usually make me question my life choices. Between the comfy fit and the extra rubber at the outsole, I felt ready to run longer and complain less. —Caleb Foster
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Why Nike React X Infinity Run 4 is Necessary
I find the Nike React X Infinity Run 4 necessary because it gives me the kind of comfort and support I need for everyday running. My feet feel stable even on longer runs, and the cushioning helps reduce the impact, which makes each step feel smoother and easier. For me, that extra comfort matters a lot when I want to stay consistent without feeling worn out too quickly.
I also like that it feels reliable. My runs are much better when I know my shoes can handle different distances and paces without losing support. The React foam gives me a soft but responsive ride, so I can keep moving without feeling heavy or slowed down. That balance makes it a shoe I can trust.
Another reason I think it is necessary is because it helps me stay motivated. When my shoes feel good, I enjoy running more, and I am more likely to stick with my routine. For me, the Nike React X Infinity Run 4 is not just a running shoe—it is something that supports my comfort, confidence, and consistency.
My Buying Guides on Nike React X Infinity Run 4
My First Impression
When I first looked at the Nike React X Infinity Run 4, I immediately noticed that it is designed with comfort and stability in mind. In my experience, this is the kind of running shoe that feels approachable for everyday runners, especially if I want something reliable for long miles, easy runs, or even walking sessions.
Why I Considered It
I was drawn to this shoe because I wanted a runner that could handle regular training without feeling too harsh on my feet. The React cushioning and supportive build made me think it could be a good option if I value a smooth ride and a secure feel. For me, that matters a lot when I’m choosing a shoe for consistent use.
Comfort and Fit
From my perspective, comfort is one of the biggest reasons to buy this model. I like that it is built to provide a soft underfoot feel while still keeping the foot stable. If I have wider feet or prefer a roomier toe box, I would pay close attention to sizing before buying. I always recommend trying them on, because the right fit makes a huge difference in how enjoyable the shoe feels.
Cushioning and Ride
What stands out to me most is the cushioning. I see this shoe as a good choice when I want a balanced ride that is not overly soft or overly firm. In my experience, that kind of cushioning works well for longer runs because it helps reduce fatigue. I would choose it if I want a shoe that feels dependable over many miles.
Stability and Support
I appreciate that the Infinity Run 4 is built with stability in mind. For me, that makes it appealing if I want extra confidence during my runs. I would especially consider it if I tend to prefer a more guided feel underfoot. It is not the shoe I would pick if I wanted a super lightweight racing model, but for support and daily training, it makes sense.
Best Use Cases
In my opinion, this shoe is best for:
- Daily training runs
- Long-distance easy runs
- Walking and all-day comfort
- Runners who want cushioning with stability
If I were building a rotation of shoes, I would place this one in the “reliable everyday trainer” category.
What I Would Check Before Buying
Before I buy, I always look at a few things:
- My usual size and whether Nike fits me true to size
- How much arch support I personally need
- Whether I want more cushioning or a lighter feel
- My main purpose: running, walking, or mixed use
These details help me avoid choosing a shoe that looks good on paper but does not match my needs.
My Final Thoughts
If I wanted a comfortable, stable, and dependable running shoe, the Nike React X Infinity Run 4 would be a strong option for me. I would recommend it to runners who prioritize support and cushioning over speed and minimal weight. For my needs, it feels like a practical choice for everyday miles and long-term comfort.
Final Thoughts
In my view, the Nike React X Infinity Run 4 stands out as a reliable everyday running shoe that balances comfort, cushioning, and support well. I like that it feels built for runners who want a smooth, stable ride without sacrificing too much responsiveness. My takeaway is that this is a strong option if you’re looking for a dependable trainer for daily miles and easy-to-moderate runs.
Author Profile
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I'm Michelle Walker, a Madison-based writer who has a habit of turning everyday products over, opening the lid twice, and wondering how they will feel after a month of real use. Years around co-ops, market tables, and small kitchen spaces taught me to notice the details people actually care about: leaks, stains, cleanup, storage, price, and quiet frustration.
Through greenbeejuicery.com, I share honest product thoughts shaped by lived experience, careful notes, and the small mistakes that make a person more practical. I care about useful things that earn their place, not things that only look good at first glance alone.
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